Interaction between Liprin- and GIT1 Is Required for AMPA Receptor Targeting
نویسندگان
چکیده
Jaewon Ko,1 Seho Kim,1 Juli G. Valtschanoff,2 Hyewon Shin,1 Jae-Ran Lee,1 Morgan Sheng,3 Richard T. Premont,4 Richard J. Weinberg,2 and Eunjoon Kim1 1Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea, 2Department of Cell Biology and Anatomy, University of North Carolina Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, 3Center for Learning and Memory, RIKEN-MIT Neuroscience Research Center and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, and 4Department of Medicine (Gastroenterology), Duke University Medical Center, Durham, North Carolina 27710
منابع مشابه
Biochemical and Functional Characterization of the Interaction between Liprin-α1 and GIT1: Implications for the Regulation of Cell Motility
We have previously identified the scaffold protein liprin-α1 as an important regulator of integrin-mediated cell motility and tumor cell invasion. Liprin-α1 may interact with different proteins, and the functional significance of these interactions in the regulation of cell motility is poorly known. Here we have addressed the involvement of the liprin-α1 partner GIT1 in liprin-α1-mediated effec...
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